Implantable defibrillators for life threatening ventricular arrhythmias

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Failure to Treat Life-Threatening Ventricular Tachyarrhythmias in Contemporary Implantable Cardioverter–Defibrillators

BACKGROUND In clinical trials, manufacturer-specific, strategic programming of implantable cardioverter-defibrillators (ICDs), including faster detection rates, reduces unnecessary therapy but permits therapy for ventricular tachycardia/ventricular fibrillation (VF). Present consensus recommends a generic rate threshold between 185 and 200 beats per minute, which exceeds the rate tested in clin...

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Role of the implantable defibrillator among elderly patients with a history of life-threatening ventricular arrhythmias.

AIMS The implantable defibrillator (ICD) reduces arrhythmic and all-cause mortality in patients with a history of life-threatening ventricular arrhythmias. However, its effectiveness in elderly patients is uncertain, given their competing risk of non-arrhythmic death. METHODS AND RESULTS Individual patient data from all three secondary prevention trials comparing the ICD to amiodarone were po...

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Can chronotropic incompetence predict life-threatening ventricular arrhythmias in patients with stable ischemic heart disease?

Background: Chronotropic incompetence has prognostic value of all-cause and cardiovascular mortality in both patients with asymptomatic and symptomatic ischemic heart disease (IHD), regardless of traditional risk factors. The aim of this study was to investigate the relationship between chronotropic response during exercise test and the development of ventricular arrhythmias. Methods: 153 pati...

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Timing of life-threatening arrhythmias detected by implantable cardioverter-defibrillators in relation to changes in cosmophysical factors.

BACKGROUND Studies have linked the natural history of many pathologies with environmental physical activity. This study investigated the relationship between the occurrence of ventricular tachycardia/fibrillation (VT/VF) recorded by implantable cardioverter defibrillators (ICD) and geomagnetic and cosmic ray (neutron) activity. METHODS The study group included 85 patients (73 men) with cardio...

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Surgical alternatives in the treatment of life-threatening ventricular arrhythmias.

We present our experience in the treatment of life-threatening ventricular tachycardia using electrophysiologically guided surgery (97 patients), automatic implantable cardioverter defibrillator (AICD) (42 patients), and orthotopic heart transplantation (15 patients). Eighty-three percent of these patients had ischemic and 17%, nonischemic heart disease. Our results of electrophysiologically di...

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ژورنال

عنوان ژورنال: BMJ

سال: 1998

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.317.7161.762